ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2014, Vol. 45 ›› Issue (4): 661-665.doi: 10.11843/j.issn.0366-6964.2014.04.022

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The Distribution of PR in Superior Cervical Ganglion of Female Goats

GUO Xiao, LI Qiang, XU Yong-ping*, JIN Xiu-fang, CHEN Wen-dong,WANG Zhi-hao, DONG Wei, FAN Jie   

  1. (College of Veterinary Medicine,Northwest A﹠F University,Yangling 712100, China)
  • Received:2013-10-09 Online:2014-04-23 Published:2014-04-23

Abstract:

In order to explore whether the superior cervical ganglion (SCG) of female goats was equipped with the conditions for the action of progesterone,thereby speculating that whether progesterone was involved in neural regulation of endocrine processes of target organs,we used immunohistochemical SP method to detect the distribution of progesterone receptor (PR) in SCG of female goat.The result showed that PR-immunoreactive-products were widely distributed in the SCG of female goat,and different levels of staining existed in neurons,Schwann cells,satellite cells and nerve fibers.All the neurons were PR positive,of which the cell membrane and cytoplasm was brown as moderate positive,and nuclei was brown as strong positive.Schwann cells,satellite and nerve fibers also had yellow,weak positive PR-positive-product.Image analysis showed that PR in the nerve cells was extremely higher (P<0.01) than other non-nerve cells.The result proved that the neurons in the SCG were the one of main target cells of progesterone,implying that progesterone may act on the sympathetic postganglionic neurons of the SCG,and thus participates in the activities of the target organ dominated by the SCG,and PR in the SCG might act as a network node to coordinate the endocrine regulation of progesterone and neuroregulation of autonomic nerve on the activities of the target organ.

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